MovDisordV3, Main, Exploration, bibRecord, 003905

Glutathione‐S‐transferase‐1 and interleukin‐1β gene polymorphisms in Japanese patients with Parkinson's disease

Identifieur interne : 003905 ( Main/Exploration ); précédent : 003904; suivant : 003906

Glutathione‐S‐transferase‐1 and interleukin‐1β gene polymorphisms in Japanese patients with Parkinson's disease

Auteurs : Masataka Nishimura [Japon] ; Sadako Kuno [Japon] ; Ryuji Kaji [Japon] ; Katsuhito Yasuno [Japon] ; Hideshi Kawakami [Japon]

Source :

Movement Disorders [ 0885-3185 ] ; 2005-07.

RBID : ISTEX:4103B303C7D2D8EBB3BBBCFAA1FB16C95AC9AEC9

Descripteurs français

Pascal (Inist)
- Glutathione transferase, Homme, Interleukine 1, Interleukine 1β, Japonais, Parkinson maladie, Polymorphisme, Système nerveux pathologie.
Wicri :
- geographic : Japon.
- topic : Homme.

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Analysis of Variance, Chi-Square Distribution, Female, Genotype, Glutathione Transferase (genetics), Glutathione transferase, Human, Humans, Interleukin 1, Interleukin 1β, Interleukin-1 (genetics), Japan (epidemiology), Japan (ethnology), Japanese, Linkage Disequilibrium, Male, Middle Aged, Nervous system diseases, Parkinson Disease (genetics), Parkinson disease, Parkinson's disease (PD), Polymorphism, Polymorphism, Genetic, Polymorphism, Restriction Fragment Length, RNA, Messenger (biosynthesis), Reverse Transcriptase Polymerase Chain Reaction (methods), age at onset, glutathione‐S‐transferase‐1 (GST‐1), interleukin‐1β (IL‐1β), polymorphism.
MESH :
- chemical , biosynthesis : RNA, Messenger.
- chemical , genetics : Glutathione Transferase, Interleukin-1.
- geographic , epidemiology : Japan.
- geographic , ethnology : Japan.
- genetics : Parkinson Disease.
- methods : Reverse Transcriptase Polymerase Chain Reaction.
- Adult, Aged, Aged, 80 and over, Analysis of Variance, Chi-Square Distribution, Female, Genotype, Humans, Linkage Disequilibrium, Male, Middle Aged, Polymorphism, Genetic, Polymorphism, Restriction Fragment Length.

Abstract

We studied genetic polymorphisms in the glutathione‐S‐transferase‐1 (GST‐1) gene region and the interleukin‐1β (IL‐1β) promoter region in patients with Parkinson's disease (PD, n = 361), as well as controls (n = 257). Although we have confirmed the previous results, in a larger sample, that the IL‐1β genotype has affected the age at onset of PD patients, no contribution of the GST‐1 gene polymorphism was observed in the allele frequency or the onset age of the disease in Japanese persons. © 2005 Movement Disorder Society

Url:

https://api.istex.fr/document/4103B303C7D2D8EBB3BBBCFAA1FB16C95AC9AEC9/fulltext/pdf

DOI: 10.1002/mds.20477

Affiliations:

Japon
Tokyo

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<term>Genotype</term>
<term>Glutathione Transferase (genetics)</term>
<term>Glutathione transferase</term>
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<term>Humans</term>
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<front><div type="abstract" xml:lang="en">We studied genetic polymorphisms in the glutathione‐S‐transferase‐1 (GST‐1) gene region and the interleukin‐1β (IL‐1β) promoter region in patients with Parkinson's disease (PD, n = 361), as well as controls (n = 257). Although we have confirmed the previous results, in a larger sample, that the IL‐1β genotype has affected the age at onset of PD patients, no contribution of the GST‐1 gene polymorphism was observed in the allele frequency or the onset age of the disease in Japanese persons. © 2005 Movement Disorder Society</div>
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Movement Disorders (revue)

Glutathione‐S‐transferase‐1 and interleukin‐1β gene polymorphisms in Japanese patients with Parkinson's disease

Glutathione‐S‐transferase‐1 and interleukin‐1β gene polymorphisms in Japanese patients with Parkinson's disease

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
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